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An Ozempic Pill Was Tested on Heavy Drinkers—the Results Were Promising

An Ozempic Pill Was Tested on Heavy Drinkers—the Results Were Promising

Summary

Researchers tested an oral diabetes and weight-loss drug called semaglutide on adults with alcohol use disorder (AUD). The study found that the drug helped reduce heavy drinking and alcohol cravings without causing weight loss, suggesting a new way to treat AUD.

Key Facts

  • Semaglutide is a medication originally for diabetes and weight loss, now used by many Americans.
  • The study involved 50 adults with AUD and lasted eight weeks.
  • Participants taking oral semaglutide drank less heavily and had fewer alcohol cravings.
  • The drug’s effect on reducing drinking did not involve weight loss or changes in eating.
  • Alcohol use disorder affects about 27 million adults in the U.S. as of 2024.
  • No new medicines for AUD have been approved in nearly 20 years.
  • Researchers believe semaglutide may work by reducing dopamine signals in the brain’s reward centers.
  • Larger and longer studies are needed before semaglutide can be recommended as an AUD treatment.
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