Fertility After 35 May Not Just Be About Eggs, Scientists Say
Summary
New research shows that fertility decline after age 35 may be linked not only to egg quality but also to changes in the bacteria living in the uterus. Scientists found that certain helpful bacteria in the womb decrease with age, which could affect a woman’s ability to become pregnant.Key Facts
- Fertility decline after 35 has traditionally been attributed to egg quality and ovarian reserve.
- The new study looked at the uterine microbiome, the community of bacteria in the womb.
- Researchers studied 149 women aged 20 to 45 who were being treated for infertility.
- Younger women had more Lactobacillus bacteria, especially Lactobacillus gasseri, than older women.
- Women who became pregnant had higher levels of these bacteria in their uterine lining.
- Lab tests showed Lactobacillus gasseri has properties that protect uterine cells from aging.
- In older mice, treatment with substances from Lactobacillus gasseri improved embryo implantation rates.
- The findings suggest fertility support after 35 may need to focus on uterus health, not only eggs.
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