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FDA approves new pancreatic cancer drug that could extend patients' lives

FDA approves new pancreatic cancer drug that could extend patients' lives

Summary

The U.S. Food and Drug Administration (FDA) has approved a new pill called daraxonrasib (brand name Rasonque) to treat advanced pancreatic cancer. This drug blocks a mutated protein causing tumor growth and has nearly doubled survival time for patients compared to chemotherapy.

Key Facts

  • Daraxonrasib targets mutated RAS proteins found in over 90% of pancreatic cancer cases.
  • The drug was approved by the FDA faster than planned, reflecting its importance.
  • Patients taking daraxonrasib lived a median of 13.2 months versus 6.7 months for those on chemotherapy.
  • Side effects include skin rash, mouth sores, diarrhea, and digestive problems.
  • Pancreatic cancer is very deadly and often diagnosed late when it has spread to other organs.
  • About 67,000 new U.S. cases are expected this year with more than 52,000 deaths.
  • Former Senator Ben Sasse, diagnosed with stage-four pancreatic cancer, reported significant benefit from the drug.
  • The pill could lead to new treatments for other cancers with similar genetic mutations.
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