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Girls Exposed to Tylenol in the Womb Showed Surprising Changes, Study Finds

Girls Exposed to Tylenol in the Womb Showed Surprising Changes, Study Finds

Summary

Scientists in Denmark studied girls whose mothers took paracetamol (Tylenol) during pregnancy and found changes in the girls’ ovarian and uterine development from infancy through adolescence. The study does not prove paracetamol caused these changes, but it suggests fetal exposure might affect female reproductive health.

Key Facts

  • Researchers followed 302 girls and their mothers’ paracetamol use during pregnancy.
  • Girls exposed to paracetamol in early pregnancy had smaller ovaries and uteruses.
  • Exposure later in pregnancy was linked to fewer ovarian follicles (egg-containing structures).
  • Some girls exposed early showed lower levels of a hormone called anti-Müllerian hormone (AMH), which relates to ovarian reserve.
  • A larger group of 1,210 girls showed similar patterns in adolescence.
  • More than half of pregnant women use paracetamol during pregnancy.
  • Animal studies have shown fetal exposure to paracetamol can reduce ovarian reserves.
  • It is still unknown whether these changes affect fertility later in life, and more research is needed.
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