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Google figures out how to watermark AI-designed proteins

Google figures out how to watermark AI-designed proteins

Summary

Google’s DeepMind team developed a way to add a hidden “watermark” to AI-designed proteins. This watermark can identify proteins made by trusted researchers without affecting how the protein works, helping to track and control potentially risky AI-made biological materials.

Key Facts

  • AI tools can create useful proteins but may also generate harmful toxins or viral proteins.
  • Current software cannot easily detect AI-designed proteins as potential threats.
  • Google’s solution is to embed a hidden code, called a watermark, directly into protein sequences.
  • The watermark does not change how the protein functions or changes its structure.
  • The method is based on Google’s SynthID technology, originally used to watermark digital materials like images and text.
  • Proteins are made of 20 amino acids, some very sensitive to changes, making watermarking challenging.
  • The team used ProteinMPNN, an AI tool for protein design, to embed these watermarks successfully.
  • This approach allows identification of proteins made by approved sources, enabling better biosecurity checks.
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