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Map Shows Where Cychlorphine-Related Deaths Are Surging Across US

Map Shows Where Cychlorphine-Related Deaths Are Surging Across US

Summary

A synthetic opioid called cychlorphine, which is about 10 times stronger than fentanyl, is causing more overdose emergencies and deaths across the U.S. It has spread quickly in several states, especially Tennessee, Texas, and other parts of the South, Midwest, and Northeast. The drug is often mixed with fentanyl, making it hard to detect with standard tests.

Key Facts

  • Cychlorphine is a synthetic opioid linked to many overdoses and deaths since last year.
  • It is about 10 times stronger than fentanyl, a well-known dangerous opioid.
  • Emergency overdoses in Austin, Texas, increased from 73 to 98 in one year, with more severe cases needing multiple Narcan doses.
  • The drug has been found mixed with fentanyl and fake pills, making it difficult for current tests to detect.
  • Cychlorphine first appeared in the U.S. in Florida in April 2024 and has since spread to multiple states.
  • In 2025, cychlorphine was detected 106 times in 10 states across all U.S. regions.
  • At least 55 deaths were linked to cychlorphine nationwide between 2025 and early 2026, with 64 deaths reported in Tennessee alone recently.
  • Experts believe the drug is present in more states but remains undetected due to limited testing.
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