Diabetes and ADHD drugs to be tested on Alzheimer's patients in new study
Summary
A new study in the UK is testing two existing drugs, one for diabetes and one for ADHD, to see if they can help people with Alzheimer's disease. The trial aims to find treatments faster by testing multiple drugs at once and checking if they improve memory, thinking, and daily living skills.Key Facts
- The study is called AD-SMART and is based in the UK.
- It tests multiple drugs at the same time, comparing results against a placebo group.
- The first two drugs being tested are metformin (for type 2 diabetes) and atomoxetine (for ADHD).
- Both drugs may help reduce brain inflammation linked to Alzheimer’s damage.
- Around 1,200 people with mild to moderate Alzheimer’s will join the trial across over 30 UK sites.
- The trial uses a flexible approach: ineffective drugs can be dropped quickly and new ones added.
- Researchers expect initial results by 2030, with further treatments tested after.
- Participants will have regular health and thinking ability checks during the trial.
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