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A new HIV-prevention drug is showing promising signs, but it's difficult to find in Africa and beyond

A new HIV-prevention drug is showing promising signs, but it's difficult to find in Africa and beyond

Summary

Lenacapavir, a long-acting HIV-prevention drug given twice a year, has shown strong protection in studies, but supply remains limited in Uganda and elsewhere. The U.S. Food and Drug Administration has tentatively approved a generic version for 120 low-income countries, which could lower the price and expand access, though advocates say current plans will not reach enough people quickly enough.

Key Facts

  • Lenacapavir is an HIV-prevention drug developed by Gilead Sciences and is administered twice a year.
  • Studies have shown that lenacapavir can provide nearly complete protection from HIV.
  • People in Mbarara, Uganda, report difficulty obtaining lenacapavir because clinics do not have enough doses.
  • The FDA has tentatively approved a generic version of lenacapavir for use in 120 low-income countries.
  • The generic version could cost about $40 per year, compared with a U.S. list price of $28,218.
  • The Global Fund hopes to provide lenacapavir to 3 million people by the end of 2028.
  • Doctors Without Borders says the planned supply and country coverage are insufficient and has urged Gilead to expand access.
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