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Cocaine overtakes heroin as leading cause of drug deaths in England and Wales

Cocaine overtakes heroin as leading cause of drug deaths in England and Wales

Summary

Cocaine was involved in 22% of drug-poisoning deaths registered in England and Wales in 2025, making it the leading drug involved in these deaths for the first time. Overall, 5,519 drug-poisoning deaths were registered, 46 fewer than in 2024, but the rate remained about twice the level of a decade earlier.

Key Facts

  • Cocaine was involved in 1,233 deaths in 2025.
  • Cocaine-specific deaths were four times higher than a decade earlier and eight times higher than in 2010.
  • People over 40 accounted for 64% of registered cocaine deaths.
  • The north-east of England had the highest drug-death rate, at 135.2 per million people; London had the lowest, at 58.3 per million.
  • Drug-death rates were five times higher in the most deprived areas than in the least deprived areas.
  • Ketamine was mentioned in 115 deaths in 2025, up from 27 in 2020 and seven in 2015.
  • Drug charities called for more action and treatment support, and criticized the government’s response.
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