Researchers Gave Adults a Daily Supplement—Then Spotted a Change in Brain
Summary
A four-week study of 50 adults with obesity found that daily urolithin A increased blood flow to the brain during a memory task, especially in a region involved in working memory. Participants did not perform better on the task, and researchers said longer studies are needed to assess possible effects on brain health.Key Facts
- The study included 50 adults ages 40 to 64 with a body mass index of 30 or higher.
- Participants took either 1,000 milligrams of urolithin A daily or a placebo for four weeks.
- Urolithin A users showed increased brain blood flow while doing a memory task.
- The blood-flow change was especially notable in a brain region involved in working memory.
- The supplement did not improve participants’ measured memory-task performance.
- Researchers reported side effects including headaches, back pain, diarrhea, nausea and vomiting; they described the supplement as generally well-tolerated.
- The study was published in JAMA Network Open on October 9.
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