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A drug originally made to fight cancer called CADD522 helped strengthen bones and reduce body fat in older female mice that no longer produce estrogen. The study suggests this drug might help women during menopause manage weight gain and bone loss, but the drug is still being tested and has only been used in animals so far.
Key Facts
CADD522 was created to block a protein that helps cancer tumors grow.
In mice without estrogen (similar to postmenopausal women), CADD522 made bones stronger and improved bone structure.
Mice given CADD522 weighed less and had less body fat despite eating the same amount as untreated mice.
The drug also reduced fat buildup inside bone marrow, which often happens after menopause and harms bones.
Researchers saw healthier fat metabolism in the brain of treated mice, which might relate to better brain health.
CADD522 was safe in tests on mice, rats, and dogs and can be taken by mouth.
The drug breaks down slower in human tissue, which could make it more effective in people.
More studies are needed to test if CADD522 works and is safe for women, especially those with bone loss or near menopause.
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Nathan Fielder, a comedian known for satire, is creating a documentary about Elizabeth Holmes. Holmes is a former business leader who was found guilty of cheating investors through her health technology company, Theranos.
Key Facts
Nathan Fielder is making a documentary called "You Can See Everything."
The documentary focuses on Elizabeth Holmes.
Holmes was a business executive linked to the company Theranos.
Theranos claimed to have revolutionary health technology.
Holmes was convicted of defrauding investors.
The film includes scenes with Holmes and Fielder interacting closely.
The documentary is being promoted with a trailer.
The project aims to explore Holmes’s story and actions.
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The Taliban are still using military gear that the U.S. left behind when its forces withdrew from Afghanistan five years ago. This equipment includes weapons and vehicles that originally belonged to the U.S. military.
Key Facts
The U.S. military withdrew from Afghanistan five years ago.
The Taliban took control of many military items left behind by the U.S.
The leftover equipment includes weapons and vehicles.
The Taliban continues to use this U.S. equipment today.
The situation shows the long-term impact of the U.S. military withdrawal.
The equipment helps the Taliban maintain their military strength.
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Hurricane Lowell is close to Hawaii, causing residents to prepare for strong winds and heavy rain. People in Hawaii are staying safe as the storm moves nearby.
Key Facts
Hurricane Lowell is near Hawaii and bringing bad weather.
The storm is expected to cause many hours of wind and rain.
Residents in Hawaii are taking shelter to stay safe.
Local news outlets are reporting on the storm’s progress.
Authorities are likely monitoring the situation closely.
The impact includes possible disruptions due to the weather.
People are advised to follow safety instructions during the hurricane.
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The European Union’s highest court ruled that a far-right Belgian party cannot use IKEA’s trademarks to promote an anti-immigration campaign because it could harm IKEA’s reputation. The court said freedom of expression does not protect using trademarks in this way unless it is done in good faith or for the public interest.
Key Facts
The Belgian party Vlaams Belang used IKEA-style logos and imagery in an anti-immigration campaign called the “IKEA Plan.”
IKEA filed a legal complaint, saying the party used its trademarks without permission.
The party’s supporters argued their use was protected by freedom of expression.
The Belgian court asked the European Court of Justice (ECJ) to rule on the case.
The ECJ found that using IKEA’s trademarks this way could harm the company’s reputation.
The court said freedom of expression only applies if trademarks are used in good faith or for public interest, which was not proven here.
The Belgian court will make the final decision but is expected to follow the ECJ’s guidance.
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Scientists found that immune cells called T cells related to brain damage in Alzheimer’s may get activated outside the brain, in lymph nodes. In mice with Alzheimer’s-like brain problems, blocking these immune cells reduced brain damage and helped preserve thinking abilities, even though the protein clumps linked to the disease stayed the same.
Key Facts
Alzheimer’s disease involves abnormal tau protein clumps in the brain called tau tangles.
T cells, a type of immune cell, build up in the brains of people and mice with Alzheimer’s and cause damage.
Researchers discovered T cells may be activated by dendritic cells in lymph nodes, not in the brain.
Removing dendritic cells from lymph nodes in mice lowered T cell numbers in the brain and reduced brain damage.
Brain tau tangles remained unchanged even when immune activity was blocked.
Mice with blocked T cell activity kept better cognitive function despite carrying tau tangles.
Material from damaged brain cells might travel to lymph nodes to trigger immune activation.
Similar immune activity involving T cells has been observed in human Alzheimer’s disease and related conditions.
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Iceland’s government asked the U.S. ambassador to explain a social media post by President Trump. The post showed a map with the American flag covering Iceland and other countries, which Iceland found inappropriate.
Key Facts
Iceland summoned the U.S. ambassador on Monday for an explanation.
President Trump posted a map on Truth Social showing the American flag over Iceland and other regions.
The map included North America, Greenland, Iceland, and Central America covered by the flag.
President Trump has previously suggested the U.S. should take over Greenland and Canada.
Iceland’s government viewed the flag covering their country as a sensitive or inappropriate act.
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The president of the United Arab Emirates reportedly warned Israeli Prime Minister Benjamin Netanyahu about a planned major attack by Hamas just days before the October 7, 2023, assault. Netanyahu’s office denied the report, which has become a key issue in Israel’s upcoming elections.
Key Facts
UAE President Mohammed bin Zayed allegedly warned Netanyahu 10 days before the attack that Hamas planned a major offensive.
The warning said the attack could cause many deaths and disrupt regional peace agreements called the Abraham Accords.
Netanyahu reportedly responded calmly and said Israel was prepared for any attack, expecting it to come from the West Bank.
Hamas killed about 1,200 people and took 251 hostages in the October 7 attack.
Netanyahu’s office called the report of the warning “an absolute lie” and said he did not speak with the UAE president at that time.
Netanyahu rejected calls for an official investigation into the events surrounding the attack.
The report is influencing Israel’s national election campaign, with Netanyahu’s rivals blaming him for poor security.
More than 73,650 Palestinians have been killed in ongoing fighting related to Israel’s offensive in Gaza.
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Thousands of people protested in Germany against the far-right party Alternative für Deutschland (AfD) after it won a large share of votes in a state election. The AfD is strong in two upcoming regional elections, raising concerns about its impact on democracy and minority rights.
Key Facts
The AfD won nearly 44% of the vote in Saxony-Anhalt, its best result ever in a state election.
Demonstrations against the AfD took place near the Brandenburg Gate in Berlin and other cities. Organizers say more than 14,000 people protested.
The AfD calls for deporting asylum seekers and reducing support for renewable energy and public broadcasting.
The party is close to forming a government in Saxony-Anhalt but needs three more votes for a majority.
Germany’s domestic intelligence agency classifies the AfD as rightwing extremist, seeing it as a threat to democracy.
The AfD leads voter polls in Mecklenburg-Western Pomerania, with about 35% support before elections on September 20.
Other parties in Berlin remain competitive, with the Christian Democrats, Social Democrats, the left-wing Linke, and Greens all polling closely.
Many protesters expressed concern that the AfD’s far-right views threaten democracy and social services.
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Russia is using the combat experience of its weapons, especially the Su-57 fighter jet, to attract international buyers at an air show in Egypt. Russian arms exports grew to over $13 billion in the first half of 2026 as Moscow markets its weapons as tested and proven in real battles, including the conflict in Ukraine.
Key Facts
Russia showcased the Su-57 fighter jet at the El Alamein air show in Egypt.
Rosoboronexport, Russia’s state arms exporter, says more than 90% of its weapons sold this year were tested against Western equipment.
Russia signed over $13 billion in new arms contracts in the first six months of 2026.
Russia’s share of global major arms exports dropped from 21% (2016-2020) to 6.8% (2021-2025) due to sanctions and war effects.
Russian weapons marketed as battle-tested include the Sarma rocket system and BTR-22 armored personnel carrier.
Other countries, like Israel and Greece, are also using battle-tested weapons to boost sales and defense agreements.
Ukraine has become a testing ground for Russian drones and missiles, with evolving effectiveness against Ukrainian defenses.
Russia launched a large drone and missile attack on major Ukrainian cities shortly after U.S. officials visited Ukraine.
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President Donald Trump said that oil prices will fall sharply after the United States wins a war with Iran. Iran is trying to control an important shipping route called the Strait of Hormuz by setting up a restricted zone.
Key Facts
President Trump spoke about oil prices and the conflict with Iran.
He predicted oil prices will drop sharply once the war with Iran ends.
Iran wants to control the Strait of Hormuz, a key path for oil shipments.
Iran is creating a restricted zone in the Strait of Hormuz.
The Strait of Hormuz is important for global oil transportation.
Trump made his statement on the social media platform Truth Social.
The situation involves ongoing tensions between the U.S. and Iran.
The comments suggest expectations of a U.S. military victory over Iran.
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Hurricane Lowell passed just west of Hawaii late Monday night, bringing heavy rain and strong winds. The storm caused power outages for tens of thousands of homes and businesses, according to the National Hurricane Center.
Key Facts
Hurricane Lowell moved near the west side of Hawaii.
The storm brought heavy rain and strong winds.
Tens of thousands of homes and businesses lost power.
The National Hurricane Center provided information about the storm.
The event happened late Monday night.
The impact affected both homes and businesses in Hawaii.
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Iryna Terekh, the CEO of Ukrainian company Fire Point, leads a team that builds long-range drones used against Russian targets. The company has grown rapidly and recently tested a cruise missile with a range over 1,000 miles and aims to launch Ukraine's first domestically made ballistic missile soon.
Key Facts
Iryna Terekh is the 34-year-old CEO of Fire Point, one of Ukraine's largest drone makers.
Fire Point started making drones after Russia invaded Ukraine in 2022.
The company produces 300 to 400 long-range attack drones per day.
Fire Point’s cruise missile flew over 1,000 miles on a recent combat mission.
Terekh says Ukraine has launched twice as many deep strikes into Russia in 2026, with 60% using Fire Point weapons.
Ukraine plans to soon deploy its first domestically designed ballistic missile, which follows a high arc trajectory.
Many Ukrainian startups have shifted the country from mainly receiving military aid to creating new defense technology.
Fire Point was founded by people from civilian backgrounds, including architecture and film production.
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Russian authorities have arrested a 21-year-old Moldovan citizen who is suspected of shooting a senior Russian military officer on the orders of Ukrainian intelligence. The officer survived the attack and remains in the hospital. This incident is one of several attacks on Russian military and government figures linked to the conflict between Russia and Ukraine.
Key Facts
A Moldovan man, age 21, was detained by Russian security for allegedly attempting to kill a Russian Defense Ministry officer.
The attack happened on September 3 near Engels city in the Saratov region, home to a major Russian air force base.
The officer was shot six times but survived and is hospitalized.
Russian authorities claim the suspect was recruited by Ukrainian intelligence in 2025 and entered Russia in June.
The suspect was caught trying to leave Russia through the Astrakhan region and was allegedly paid $70,000 for the attack.
These attacks follow several other incidents targeting Russian military personnel and officials since the war with Ukraine escalated in 2022.
Ukrainian security services have claimed responsibility for some attacks inside Russia, including the assassination of a senior Russian general using an explosive device.
Russian President Vladimir Putin previously ordered tighter security around military and government officials due to these threats.
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A strong El Niño weather pattern, combined with conflicts and shipping problems, is raising global food prices and disrupting supplies. Experts warn that these challenges will continue through 2026 and may cause higher costs for groceries worldwide.
Key Facts
The United Nations says world food prices in August 2024 were the highest since 2022.
The ongoing El Niño event is expected to be much stronger than those recorded since 1950.
The World Meteorological Organization says El Niño will likely last until at least February 2027 and cause more droughts and floods.
The El Niño event is contributing to forest fires in Indonesia, which is the largest producer of palm oil.
Palm oil prices have risen about 24% in 2024 due to the fires and climate impacts.
Rising palm oil costs are expected to increase prices of other vegetable oils like sunflower, soy, and canola.
Conflicts in Europe and Asia are also disrupting food supplies and shipping routes.
Economists warn that damage to crops, energy supply, and trade routes will drive food prices higher globally.
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A type of skin fungus that causes itching and does not respond well to regular medicine has spread to 29 countries. The number of infections has increased three times in a short period.
Key Facts
The fungus causes itchy skin infections called ringworm.
It does not respond well to usual treatments, meaning it is drug-resistant.
The fungus has been found in 29 different countries.
The number of cases has tripled in recent years.
This spread makes it harder to control and treat the infections.
Scientists studied the fungus to understand its growth and resistance.
Drug resistance means the medicines normally used are less effective or do not work.
The increase in cases poses a concern for public health officials.
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The UK government, led by Foreign Secretary Ed Miliband, has declared Israel’s occupation of the West Bank as fully unlawful. The UK is imposing new sanctions on trade and services linked to Israeli settlements, accusing settler groups of ethnic cleansing with government support.
Key Facts
The UK calls the Israeli occupation of the West Bank unlawful in its entirety for the first time.
The UK, along with France and Canada, has banned imports from Israeli settlements in the occupied territories.
Sanctions will target services like construction and financing of settlements, and advertising of illegal settlement properties in the UK.
Personal sanctions will be applied to individuals accused of promoting violence by settlers.
The UK will also ban exports, including arms, that support the occupation.
The actions are a response to plans to expand the E1 settlement, which could further divide the West Bank.
Miliband called the situation “ethnic cleansing” carried out by settler terrorists with Israeli government backing.
Other European countries, including the Netherlands and Ireland, have also banned goods from Israeli settlements.
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Authorities in Rome have unveiled a large, ancient fresco and mosaic from the 1st century AD. These artworks, showing a maritime city, were found underground at the Baths of Trajan and have been restored for limited public viewing.
Key Facts
The fresco and mosaic were discovered in the 1990s during excavations under the Baths of Trajan, near the Colosseum in Rome.
The fresco shows a walled port city from a bird’s-eye view but the city's exact identity is unknown.
The mosaic measures about 15 meters high and has detailed decorations, including architectural elements and figures.
The Baths of Trajan were dedicated by Emperor Trajan in 109 AD and were once the world’s largest bath complex.
The artworks are opening to the public in small groups to test how they handle humidity and climate before wider access.
The site also includes a large semicircular upper-level "library," possibly part of the original bath complex.
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President Donald Trump posted an edited video on his Truth Social account showing King Charles appearing to ignore a grocery store worker who fainted. The original footage, from 2020, actually shows King Charles stopping to help the man and showing concern.
Key Facts
The edited video was posted on President Trump’s Truth Social account on Labor Day.
The clip makes it look like King Charles ignored a fainting grocery store employee.
The original video was filmed in July 2020 at a grocery distribution center in Bristol, England.
In the full video, King Charles stays with the employee and others come to help.
President Trump has described King Charles as a friend and praised him recently.
Buckingham Palace did not comment on the edited video when asked.
The video was part of a montage comparing world leaders unfavorably to President Trump.
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An 83-year-old man in Scotland was jailed for collecting over two million child abuse images, the largest such collection found by police in the country. Alan MacPherson admitted to downloading and sharing illegal images over 14 years and will be supervised for three years after his four-year prison sentence.
Key Facts
Alan MacPherson, aged 83, was found with more than two million child abuse images on multiple devices.
Over 805,000 of the images were confirmed to show child sexual abuse, much of it very serious.
Police identified MacPherson after tracing his internet address while he shared illegal images with an undercover officer.
The images mainly involved girls aged 9 to 15, with some victims possibly as young as 7.
MacPherson was sentenced to four years in jail and will be on the sex offenders register for life.
He will also be supervised for three years after his release.
MacPherson admitted to collecting images for personal reasons over 14 years.
His defense mentioned his failing eyesight and that his family has distanced themselves from him.
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