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Does this disappearing organ hold the secret of longevity?

Does this disappearing organ hold the secret of longevity?

Summary

The thymus is an organ under the breastbone that shrinks with age and helps the immune system by producing T cells. New research using AI and medical scans links a healthier thymus to longer life and better cancer treatment, but scientists still need to confirm if keeping the thymus healthy directly causes these benefits.

Key Facts

  • The thymus is located beneath the breastbone and is larger in newborns but shrinks starting in childhood.
  • It produces T cells, which are white blood cells that fight infections and cancer.
  • The thymus begins shrinking early in life and loses function as people age.
  • Harvard researchers used AI to study thousands of CT scans and found that healthier thymus tissue is associated with longer life and less heart disease and cancer.
  • A separate study linked thymus health to better responses to cancer immunotherapy.
  • People who had their thymus removed had higher risks of death and cancer, but this does not prove the thymus causes better health.
  • Scientists caution that healthier people may naturally keep a better thymus, so cause and effect are not yet confirmed.
  • Research is ongoing to see if preserving or restoring the thymus can improve immune health and longevity.
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